Cassano delle Murge is a southern Italian commune (comune) with 14,732 inhabitants (as of December 31, 2015) in the metropolitan city of Bari in Puglia. The municipality lies within the Murgia about 27 kilometers southwest of Bari and about 28 northeast of Matera. Under protection is the nearby forest area Foresta Mercadante (about 10 square kilometers [1083 hectares]).